Guinea Pig Lying on Side Twitching: Reasons & Solutions

Guinea pigs rest on their sides If they are exhausted. They also make abrupt movements when they are excited. However, if the twitching continues and does not cease, it might be a sign of something hazardous.

So why is a guinea pig lying on side twitching?

If twitching starts while resting on his side, it might indicate a health problem. Particularly if it is accompanied by respiratory distress or drooling and panting. Mites, heatstroke, head injury anything can trigger this behavior. In this case, your guinea pig is sick and should be seen by a vet.

I have gathered all the health issues that can encourage this behavior for your pet.

Continue reading and find all your answers.

Is Guinea Pig Lying and Twitching Dangerous?

Is Guinea Pig Lying and Twitching Dangerous

There are various causes for guinea pig twitching. Some of these are typical behavior and others of which may be fatal for the little pet.

It might be a significant and life-threatening issue that could result in death. You should rush to the closest pet clinic and clarify everything in depth. And help your guinea pig recover before it’s too late.

What Causes Guinea Pig Twitching?

What Causes Guinea Pig Twitching

Guinea pigs are little creatures that need special attention and care to be healthy.

Regardless of how well you look after them. And supply the most nutrition-rich meals for a balanced diet.

Your guinea pig might become unwell and unhealthy for a variety of reasons. In the worst-case situation, you may lose your beloved guinea pig companion.

Dandruff And Mites

A skin parasite infection is the most prevalent cause of a guinea pig twitching, weeping, or slumping to one side. Guinea pig mange is the term for this skin infection.

But how do you know if it is affected by guinea pig mange?

If your guinea pig sobs, leans to one side, and twitches, it is most likely afflicted with guinea pig mange. The extreme itching sensation is generated by the parasites burrowing into the skin. Which causes seizure-like activity.

Mites and a natural covering of hair are possible in certain guinea pigs. Hair loss will appear in spots on other guinea pigs. The guinea pig can go bald throughout the majority of its body in a few weeks.

They scrape with their mouth and claws to relieve the itching.

Thus, they lose their fur and develop bald patches. Even after the treatment, these bald areas take a while to regenerate fur.

Some guinea pigs are so seriously afflicted that they can’t get rid of it and need monthly medication to keep healthy. Ectoparasites are a sort of mite that resides on the guinea pig’s skin surface. It is visible and may be healed in a short amount of time.


Even little termites have the potential to grow to be dangerous and life-threatening. To get rid of mites and dandruff, use these ways-

  • Vitamin C supplementation is necessary.
  • Washing and cleaning them properly regularly. Which includes washing their ears, trimming their nails, and cleaning their cage.
  • Tick and flea powders, as well as shampoos, should be avoided. Since they contain chemicals that are toxic to guinea pigs.
  • Spray guinea pigs with Anti-Mange to get rid of the mites.
  • They need daily ivermectin dosages of 1/3 behind the ears and 1/3 in the buttocks. The buttocks are the area of the rear on which it sits or rests.

Heat Stroke

Guinea pigs are very temperature sensitive because of their thick fur, and petite physique. Heatstroke may occur not just when they are exposed to the sun. But also when they are dehydrated and hot inside.

Heatstroke may strike guinea pigs in as little as 10-15 minutes. Heatstroke in guinea pigs occurs when the temperature rises over 65-70 degrees Fahrenheit. While temperatures beyond 80 degrees might result in death.

But how can you tell if your guinea pig is having a heat stroke?

When they suffer from heatstroke, they begin to twitch and have convulsions. Dehydration, fast breathing, drooling, and panting are all present. These are all indications of heat exhaustion.

Their chin becomes drenched. They may lose their hunger or refuse to eat at all. When this occurs, you’ll notice the absence of energy and an inability to move.


You can’t do much to help yourself if you have a heatstroke. To rescue your pet, you must run to the veterinarian.  However, you can prevent this from occurring to your guinea pig.

Follow the following methods to do so.

  • Give them plenty of water to stay hydrated.
  • Put pebbles in their cage so they may cool down by sitting on them.
  • Fill their water bottle with clean, fresh water.
  • Bring them indoors when they’re in direct sunlight.
  • They should be sprayed with cold water or bathed in lukewarm water.
  • Place ice in their cage after wrapping it in a wet cloth.
  • Using a damp towel, rub their feet.
  • Place them in the coldest part of the home, preferably with a shadow.

Head Injury

they have a very tiny and sensitive body. A brain injury may be highly devastating, and they may not survive the trauma. 

This damage may cause their nerves and brain tissues to enlarge, halting respiration and digesting. Which can result in causing uncontrollable twitching.

A brain injury in a guinea pig may cause a shift in eye movement. Similar to darting eye motions. They may vomit and have a reduction in appetite. When they are traumatized, their eye may become enlarged or constricted.


You have to maintain a close look at your guinea pig, as they are very sensitive. Make sure not to place them on any higher surfaces as they might fall. Also, be careful when you are carrying it around.

Guinea Pigs are Depressed or Afraid

The guinea pig’s twitching might be triggered if it is sad or scared. When they are alone at home or get little care, they become easily melancholy. To be joyful, they need regular affirmation and attention, as well as everyday playing.

If there is a larger animal in the home that scares them, they are likely to twitch. There’s even music made specifically for the treatment of sad guinea pigs.


Try to maintain them in a different area. Where they will not be frightened by the bigger pet. Get them a second guinea pig to keep them company when they’re lonely. When they’re alone at home, they have someone with whom they may play.


Do muscle spasms happen in guinea pigs?

Calcium shortage can cause muscular spasms and tremors in guinea pigs. If the insufficiency isn’t detected and treated early enough, death might occur abruptly.

What causes guinea pigs to die suddenly?

Pneumonia, or lungs inflammation, is a common cause of mortality in guinea pigs. In guinea pigs, pneumonia is generally caused by a bacterial infection.

What is causing my guinea pig to jump and walk?

Bunny hopping might indicate a lack of vitamin C in the diet or inadequate absorption. A deficiency may induce bleeding in the joints, resulting in inflammation. Another probable reason is a calcium deficiency, which may lead to joint issues.


Now you know why your guinea pig lying on side twitching. Guinea pigs are very sensitive and need a lot of attention. Always keep a keen eye on their health.

See a vet as soon as possible to minimize the risks of worsening the situation.

Till next time, best of luck!

Ryan Dugan
Ryan Dugan
Ryan Dugan

Ryan Dugan is a dedicated pet care professional who offers top-notch services for a variety of pet species. He has a soft spot for my own feline companion, Sophie. He is passionate about animals He shares his knowledge and experience on his blog to help other pet owners understand and care for their own beloved companions. Whether you need a pet-sitting service or advice on pet care, He is the go-to expert.

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